美国戴安Dionex Acclaim Trinity P1 Series 液相色谱柱

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产品名称: 美国戴安Dionex Acclaim Trinity P1 Series 液相色谱柱

产品型号: Acclaim Trinity P1 Series

产品展商: 戴安Dionex

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简单介绍

戴安公司生产的仪器主要有离子色谱仪、高效液相色谱仪、快速溶剂萃取仪和氨基酸直接分析仪。其中离子色谱仪凭借着雄厚的技术优势和方法已广泛地应用于各个领域，其市场占有率达80%。全球与离子色谱相关的文章有90%均出自戴安公司生产的离子色谱仪。　　戴安公司的快速溶剂萃取仪15分钟之内仅用15毫升溶剂既可完成对10g样品的萃取，该技术已在环境、**、食品和聚合物工业等领域得到广泛应用。

美国戴安Dionex Acclaim Trinity P1 Series 液相色谱柱 的详细介绍

Acclaim Trinity P1 Series

Acclaim Trinity P1 is a unique, high-efficiency, silica-based column designed for pharmaceutical applications such as simultaneous separation of pharmaceutical drug substances and their counterions. This new column, based on nanopolymer silica hybrid (NSH) technology, provides multiple retention mechanisms including reversed-phase, anion-exchange, and cation-exchange. As a result, its selectivity can be easily optimized by adjusting mobile phase buffer concentration, pH, and solvent content concurrently or independently. The NSH technology ensures distinctive spatial separation of the anion-exchange and cation-exchange regions, which results in maximum flexibility in method development. The easy-to-optimize selectivity can be used to accelerate chromatographic separations and increase productivity.

NSH Chromatographic Features

Multiple retention mechanisms including reversed-phase, anion-exchange, and cation-exchange
Adjustable selectivity by mobile phase ionic strength, electrolyte type, pH, and organic solvent
Ideal selectivity for simultaneous separation of basic, neutral, and acidic analytes
Separation of hydrophilic ionic and ionizable analytes without ion-pairing reagents

Acclaim Trinity P1 Applications

Active pharmaceutical ingredients (API) and counterions (cations or anions)
Screening of pharmaceutical counterions. Both UV and evaporative light scattering (ELS) detectors, in series, are required for simultaneous determination of both drug substances and counterions.
Mixture of acidic and basic drug substances and respective counterions
Drug substances of acidic, basic, and neutral mixtures
High throughput analysis following optimization of the selectivity and resolution. The flow rate can then be increased, and the analysis time shortened.

技术参数：

Acclaim Trinity P1 Column – Superior Performance for Pharmaceutical Applications Specifications
Column chemistry	SCX, WAX and RP Mixed-Mode
Operating pressure limit (recommended)	4500 psi (4000 psi)
Operating pH range (recommended)	2.5 – 7.0 (3.0 to 6.2)
Operating flow rate range (recommended)	0.3 – 1.5(0.4 – 0.8) mL/min for 3.0-mm i.d. formats 0.15 – 0.80 (0.2 to 0.4) mL/min for 2.1-mm i.d. formats

订购信息：

Analytical Columns
Acclaim Trinity P1, 3µm, 3.0 x 150mm	075563
Acclaim Trinity P1, 3µm Analytical, (3.0 x 100mm)	071387
Acclaim Trinity P1, 3µm Analytical, (3.0 x 50mm)	071388
Acclaim Trinity P1, 3µm, 2.1 x 150mm	075564
Acclaim Trinity P1, 3µm Analytical, (2.1 x 100mm)	071389
Acclaim Trinity P1, 3µm, 2.1 x 50mm	075565

Guard Columns
Acclaim Trinity P1, 3µm Guard Cartridges, (3.0 x 10mm), 2ea (Use Holder V-2)	071390
Acclaim Trinity P1, 3µm Guard Cartridges, (2.1 x 10mm), 2ea (Use Holder V-2)	071391
Acclaim SST Guard Cartridge Holder V-2	069580
Acclaim Guard Kit (Holder and coupler) V-2	069707
Guard to Analytical Column Coupler V-2	074188

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